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SPS Journal Club is organising a talk by Dr. Manidipa Banerjee

SPS Journal Club is organising a talk by Dr. Manidipa Banerjee

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SPS Journal Club is organising a talk by Dr. Manidipa Banerjee
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SPS Journal Club

 

Title: Recent advances in cryoelectron microscopy based structural analysis

 

Date : 16th Nov (Thursday)
Time : 5 PM
Venue : Seminar Room, SPS, JNU

 

Speaker: Dr. Manidipa Banerjee,
Associate Professor, Kusuma School of Biological Sciences, IIT– Delhi

 

Abstract: The last few years has seen unprecedented progress in the field of cryoelectron microscopy and image processing, with the resolution and size barriers being broken. Central to these efforts has been the development of equipment and methods such as direct electron detector, phase pate and in-column filters, in addition to the availability of powerful microscopes and better algorithms for data collection and processing.  Currently, cryoelectron microscopy can routinely generate detailed structural information of proteins at resolutions of 2 - 3 Å, which was previously possible only through X-ray crystallography. In addition, although cryoEM was previously applicable for larger proteins complexes exclusively, high resolution structure of biomolecules less than 100 KD are frequently being resolved. Since cryoEM based structural analysis requires significantly less sample and time compared to other structural biology methods, it is expected to revolutionize the field of structural biology and forever alter the landscape of structure-based drug design. The current scenario international and national scenarios, in context of the recent Nobel prize, will be discussed.

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.