
Pankaj Kumar Giri
Assistant Professor
Centre/School/Special Centre
School of Life Sciences
Email
giripankaj@jnu.ac.in, giripankaj@mail.jnu.ac.in
Personal Webpage
Qualifications
Ph.D. from National University of Singapore, Singapore, in 2012
Areas of Interest/Specialization
Gene regulation and Epitranscriptomic Dynamics in Human Disease
Experience
- Assistant Professor, School of Life Sciences, Jawaharlal Nehru University, New Delhi, INDIA
- Assistant Professor and Ramalingaswami Fellow, SAU, New Delhi
- Postdoctoral Research Scientist, Columbia University, New York, USA
- Postdoctoral Research Associate, The Scripps Research Institute, USA
- Teaching Assistant, National University of Singapore, Singapore
Awards & Honours
- "Start-up Research Grant (SRG)", from Science and Engineering Research Board(SERB), Department of Science and Technology, Government of India,2019.
- "Ramalingaswami Re-entry fellowship", Department of Biotechnology, Government of India, 2019.
- "ACA meeting 2011 Travel Grant" by American Crystallographic Association, USA, 2011.
- "Global Scholarship for Research Excellence" by The Chinese University of Hong Kong, Hong Kong, 2011.
- "NUS Research Scholarship" to pursue Doctoral studies at National university of Singapore, Singapore 2007 -2012.
- "ICMR-Research Fellowship" by Indian Council of Medical Research, Government of India, 2006.
- "MHRD-GATE Scholarship" by Ministry of Human Resources Development (MHRD), Government of India, 2006.
International Collaboration/Consultancy
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Best Peer Reviewed Publications
- Alam S, Giri PK#. Emerging Role of m6A modification in Ovarian Cancer: Progression, Drug Resistance, and Therapeutic Prospects. Front Oncol.2024 Feb 14;1366223 doi: 10.3389/fonc.2024.1366223[Impact Factor-6.224]
- Alam S, Giri PK#. Novel players in the development of chemoresistance in ovarian cancer: ovarian cancer stem cells, non-coding RNA and nuclear receptors. Cancer Drug Resist. 2024 Feb 28;7:6. doi: 10.20517/cdr.2023.152. PMID: 38434767; PMCID: PMC10905178. [Impact Factor-3.7]
- Hu R, Hameed UFS, Sun X, Moorthy BS, Zhang W, Jeffrey PD, Zhou L, Ma X, Chen F, Pei J, Giri PK, Mou Y, Swaminathan K, Yuan P. A NR2E1-interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells. Cell Proliferation. 2023 Jan;56(1):e13350. doi: 10.1111/cpr.13350. Epub 2022 Nov 2. PMID: 36321378; PMCID: PMC9816925. [Impact Factor-8.775]
- Rothschild G1*, Zhang W1*, Lim J1*, Giri PK2, Laffleur B, Chen Y, Fang M, Chen Y, Nair L, Liu ZP, Deng H, Hammarström L, Wang J, Basu U., Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination. Science Immunology, 2020 Feb 7;5(44):eaay5864. [second author, Impact Factor-30.658]
- Lim, J*.; Giri, P. K.*#; Kazadi, D.; Laffleur, B.; Zhang, W.; Grinstein, V.; Pefanis, E.; Brown, L. M.; Ladewig, E.; Martin, O.; Chen, Y.; Rabadan, R.; Boyer, F.; Rothschild, G.; Cogné, M.; Pinaud, E.; Deng, H.; Basu, U.#, Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry. Cell 169 (3), 523-537.e15. . [ *-Co-first authors, #-Co-Corresponding Author] [Impact Factor-66.58]
- de Vera IMS, Munoz-Tello P, Dharmarajan V, Marciano DP, Matta-Camacho E, Giri PK, Shang J, Hughes TS, Rance M, Griffin PR, Kojetin DJ. (2018) Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1. Structure 2019 Jan 2; 27(1):66-77.e5. [Impact Factor-5.7]
- de Vera, I.M.S.*, Giri, P.K*., Munoz-Tello, P., Brust, R., Fuhrmann, J., Matta-Camacho, E., Shang, J., Campbell, S., Wilson, H.D., Granados, J., et al. (2016). Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1. ACS Chemical Biology 11, 1795-1799. [ *-Co-first authors] [Impact Factor-4.0]
- Hughes TS, Giri P.K., de Vera IM, Marciano DP, Kuruvilla DS, Shin Y, Blayo AL, Kamenecka TM, Burris TP, Griffin PR, Kojetin DJ.(2014) An alternate binding site for PPARγ ligands. Nature Communications 2014 Apr 7; 5:3571[Impact Factor-16.6]
- Giri P.K., Song FJ, ShanmugamMK, DingJL, Sethi G, Swaminathan K, Sivaraman J (2012) NMR structure of Carcinoscorpiusrotundicaudathioredoxin related protein 16 and its role in regulating transcription factor NF-κB activity .Journal of Biological Chemistry (JBC) 2012 Aug 24; 287(35): 29417-28[Impact Factor-4.8]
- Giri P.K., Tang X, Thangamani S, Shenoy RT, Ding JL, Swaminathan K, SivaramanJ (2010) Modifying the substrate specificity of Carcinoscorpius rotundicauda serine protease inhibitor domain 1 to target thrombin. PLoS One 2010,5: e15258[Impact Factor-3.7]
#-Corresponding author, *-equal contribution
Recent Peer Reviewed Journals/Books
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Patents (if any)
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